Includes index.

Includes bibliographical references and index.

Chapter 1. Introduction Chapter 2. An Overview of Biological Basics Chapter 3. An Overview of Chemical Reaction Analysis Chapter 4. Batch Reactor Chapter 5. Ideal Flow Reactors Chapter 6. Kinetic Theory and Reaction Kinetics Chapter 7 Parametric Estimation Chapter 8. Enzymes NEW! Chapter 9. Allosteric Enzymes and Regulations 9.1. Reactions in Life 9.2. Allostericity and cooperativity 9.2.1 Single binding site and saturation binding 9.2.2 Multiple binding sites and Morpheein mechanism 9.3. Enzyme binding and transport 9.4. Kinetics of allosteric enzyme 9.5. Allosteric regulations 9.6. Summary Recommended Reading Materials Problems NEW! Chapter 10. Adsorption 10.1 Introduction 10.2 Thermodynamics of adsorption 10.3 Ideal surface and Langmuir adsorption 10.3.1 Collision theory and adsorption rate 10.3.2 Langmuir adsorption isotherm 10.4 Idealization of non-ideal adsorption and multilayer adsorption 10.4.1 Idealization of non-uniform surface and surface interaction 10.4.2 Multilayer adsorption kinetics 10.4.3 Adsorption isotherm 10.4.4 BET isotherm 10.5 Pore Size and Surface Characterization 10.6. Applications of adsorption 10.7 Summary Recommended Reading Materials Problems Chapter 11. Catalysis and Chemical Reactions on Solid Surfaces Chapter 12. Cell Growth and Metabolism Chapter 13. Kinetics of Cell Growth and Batch Cultivation Chapter 14. Cell Growth and Fermentation Chapter 15 Ideal Fed-Batch Reactor Chapter 16. Evolution and Genetic Engineering Chapter 17. Sustainability: Perspective Chapter 18 Sustainability and Stability Chapter 19. Mass Transfer Effects: Immobilized and Heterogeneous Reaction Systems Chapter 20. Bioreactor Design & Operation NEW! Chapter 21. Bioprocess Kinetics Experimental Design 21.1 Introduction 21.2 Identification of objectives 21.3 Experimental design 20.4 Model construction 20.5 Summary Reading Materials Problems NEW! Chapter 22. Bioprocess Safety 22.1 Introduction 22.2 Chemicals and materials safety 22.3 Biosafety 22.4 Chemical process hazard 22.5 Bioprocess hazard 22.6 Reactive hazard 22.7 Summary Reading Materials Problems

Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems.